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Integrative Cardiovascular Physiology Laboratory

The Integrative Cardiovascular Physiology Laboratory (ICPL) is under the direction of Dr. Demetra Christou, Assistant Professor. The mission of the ICPL is to perform high quality original research in humans from an integrative (systemic to molecular) perspective and to provide rigorous research training to undergraduate and graduate students.

Research interests of the ICPL include: 

  • Alterations in cardiovascular-autonomic function (e.g., endothelial dysfunction, arterial stiffness) in humans with elevated cardiovascular disease risk (e.g., aging, obesity, metabolic syndrome, diabetes);
  • Mechanisms responsible for these changes (e.g., oxidative stress, chronic low grade inflammation, renin-angiotensin aldosterone system);
  • Effects of lifestyle interventions (e.g., exercise training, antioxidant, anti-inflammatory supplements) on cardiovascular-autonomic function).

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